Research Associate

(Jupiter, FL) Company Overview Founded in November 2016, Expansion Therapeutics, Inc. is a private company focused on the discovery and development of ribonucleic acid (RNA) targeted small molecule medicines. Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes. Expansion is focused on expansion repeat disorders, which are responsible for over 30 neurological and neuromuscular diseases, and for which there are currently no satisfactory therapies. Our initial disease focus, myotonic dystrophy type 1 (DM1), is the most frequent cause of adult onset muscular dystrophy. Expansion Therapeutics’ proprietary technology is based on pioneering work from the lab of Dr. Matthew D. Disney of The Scripps Research Institute Florida. In January 2018, we closed $55.3 million in Series A financing, co-led by 5AM Ventures, Kleiner Perkins, Novartis Venture Fund, and Sanofi Ventures with participation from RA Capital Management and Alexandria Venture Investments. The financing will allow Expansion to advance our portfolio of novel RNA-targeted small molecule medicines to treat rare diseases. With facilities in San Diego, California and Jupiter, Florida, Expansion Therapeutics currently employs 20 individuals in the U.S. It also has a seven-member board of directors, and six-member scientific advisory board comprised of leaders in the field of RNA-targeted small molecule chemistry and biology, RNA folding and structural biology. Additional information about the company is available at www.expansionrx.com. Position Summary Perform non-routine and semi-complex research in the laboratory as a Research Associate applying relavant knowledge and techniques to support the Scientific staff. Essential Functions • Run FRET-based in vitro assays, absorbance-based in vitro assays • Perform mammalian cell culture, including primary cells • Isolate RNA/DNA from cells and tissues • Run RT-PCR, gel electrophoresis • Assist in processing of tissue samples • Assist with genotyping and colony maintenance • Record experimental data • Present data and analysis both orally and in writing • Support upkeep and maintainance laboratory equipment • Support with preparation and placement orders for laboratory reagents • Perform other duties as assigned

Qualifications • Bachlelor’s degree in a relevant scientific discipline and proven experience in biochemical, molecular and cellular techniques • At least three years additional research experience in an industrial or academic setting • Previous experience with mammalian cell culture • Excellent oral and written communication and interpersonal skills • Ability to process and interpret data • Ability to adapt in a fast-paced environment • Ability to work effectively both independently and as a member of a team How to Apply Interested candidates should submit their cover letter and CV to careers@expansionrx.com
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